Tissue expression
Cell line expression
Protein structure
TRIP4
Thyroid hormone receptor interactor 4ASC-1, HsT17391, ZC2HC5
This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). [provided by RefSeq, Apr 2016]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| St John's Laboratory | Polyclonal |
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| Cusabio Biotech Co., Ltd | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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