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- Antigen structure
- References [5]
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- Immunohistochemistry [1]
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- Product number
- ABIN2845720 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 48-79), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 48-79, N-Term
- Antibody clone number
- RB0680
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage.
The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.
Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.
A transcriptional corepressor of Stat1 with an essential LXXLL signature motif.
Inhibition of Stat1-mediated gene activation by PIAS1.
Shima H, Suzuki H, Sun J, Kono K, Shi L, Kinomura A, Horikoshi Y, Ikura T, Ikura M, Kanaar R, Igarashi K, Saitoh H, Kurumizaka H, Tashiro S
Journal of cell science 2013 Nov 15;126(Pt 22):5284-92
Journal of cell science 2013 Nov 15;126(Pt 22):5284-92
The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.
Albor A, El-Hizawi S, Horn EJ, Laederich M, Frosk P, Wrogemann K, Kulesz-Martin M
The Journal of biological chemistry 2006 Sep 1;281(35):25850-66
The Journal of biological chemistry 2006 Sep 1;281(35):25850-66
Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.
Imoto S, Sugiyama K, Muromoto R, Sato N, Yamamoto T, Matsuda T
The Journal of biological chemistry 2003 Sep 5;278(36):34253-8
The Journal of biological chemistry 2003 Sep 5;278(36):34253-8
A transcriptional corepressor of Stat1 with an essential LXXLL signature motif.
Liu B, Gross M, ten Hoeve J, Shuai K
Proceedings of the National Academy of Sciences of the United States of America 2001 Mar 13;98(6):3203-7
Proceedings of the National Academy of Sciences of the United States of America 2001 Mar 13;98(6):3203-7
Inhibition of Stat1-mediated gene activation by PIAS1.
Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K
Proceedings of the National Academy of Sciences of the United States of America 1998 Sep 1;95(18):10626-31
Proceedings of the National Academy of Sciences of the United States of America 1998 Sep 1;95(18):10626-31
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Supportive validation
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
