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LearnBS7590
antibody from Bioworld Technology, Inc
Targeting: HIF1AN
DKFZp762F1811, FIH1, FLJ20615, FLJ22027
Western blot
Immunocytochemistry Immunoprecipitation Immunohistochemistry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS7590 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- HIF1AN polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human HIF1AN.
- Description
- Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1Ï«. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the ÉÇ-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1Ï«. This hydroxylation event blocks the association of HIF-1Ï« with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1Ï«.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of HIF1AN polyclonal antibody
