Antibody data

Product number
BS60942 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IL18RAP polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human IL18RAP.
Description
Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-g production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin£ªs disease cell lines, and does not bind IL-1Ï« or IL-1ÉÇ. The association of IL-18 to IL-18R leads to activation of NF°ÙB. At present two subunits of IL-18R have been characterized: IL-18RÏ« and IL-18RÉÇ. IL-18RÏ« has been described as the ligand-binding chain and IL-18RÉÇ as the signal-transduction chain.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL18RAP protein structure - BS60942 shown in red.