Explore
Validate
Learn
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 363302 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#363302, RRID:AB_2564189
- Product name
- Purified anti-human GPR83
- Antibody type
- Monoclonal
- Antigen
- DNA vaccine with full coding sequence of human GPCR cloned in expression vector.
- Description
- GPR83, also known as GIR, is a seven-pass membrane protein that belongs to the G-protein coupled receptor 1 family. GPR83 is an orphan GPR homologous to tachykinin and neuropeptide Y (NPY) receptors. GPR83 is expressed in the brain and in both murine and human Treg cells. GPR83 is reported to regulate core body temperature and there are four isoforms of GPR83. Studies have suggested that isoform-4, but not isoform-1, is associated with the suppressive functions of Treg cells. The precise role of GPR83 in Treg function is unclear.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- K07JP05
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- GPR83 transfected CHO-K1 cells were stained with purified anti-human GPR83 (clone K07JP05, filled histogram), or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
- Conjugate
- Unconjugated
