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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- GTX120508 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX120508, RRID:AB_10728801
- Product name
- TRIT1 antibody [N1C1]
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
Submitted references Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA.
Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor.
Yarham JW, Lamichhane TN, Pyle A, Mattijssen S, Baruffini E, Bruni F, Donnini C, Vassilev A, He L, Blakely EL, Griffin H, Santibanez-Koref M, Bindoff LA, Ferrero I, Chinnery PF, McFarland R, Maraia RJ, Taylor RW
PLoS genetics 2014 Jun;10(6):e1004424
PLoS genetics 2014 Jun;10(6):e1004424
Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor.
Lamichhane TN, Mattijssen S, Maraia RJ
Molecular and cellular biology 2013 Dec;33(24):4900-8
Molecular and cellular biology 2013 Dec;33(24):4900-8
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE GTX120508 diluted at 1:1000
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using TRIT1(GTX120508) antibody at 1:500 dilution.
