BS7795

antibody from Bioworld Technology, Inc
Targeting: ERCC2 EM9, MAG, MGC102762, MGC126218, MGC126219, XPD
Provider product page for BS7795
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7795 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ERCC2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ERCC2.
Description
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of 5 subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ERCC2 protein structure - BS7795 shown in red.