Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS7958 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- RNASE1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human RNASE1.
- Description
- RNase1 (ribonuclease, RNase A family, 1 (pancreatic), Rib1) gene encodes a 156 amino acid member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNase 1 endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. RNase 1 prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. RNase 1 is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. RNase1 is a digestive enzyme that has been recognized to be one of the most attractive model systems for molecular evolutionary studies. The RNase1 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 14q11.2, where it is linked to seven other RNase A superfamily genes. The entire RNase A cluster spans 368 kb.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of RNASE1 polyclonal antibody