Explore
Validate
Learn
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Other assay [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MA5-14215 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- MMP7 Monoclonal Antibody (ID2)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-14215 targets MMP-7 (Matrilysin) in IF applications and shows reactivity with Human samples.
- Antibody clone number
- ID2
- Concentration
- 0.2 mg/mL
Submitted references Relationship between Metalloprotease-7 and -14 and Tissue Inhibitor of Metalloprotease 1 Expression by Mucosal Stromal Cells and Colorectal Cancer Development in Inflammatory Bowel Disease.
Expression and Clinical Significance of Metalloproteases and Their Inhibitors by Endothelial Cells From Invasive Breast Carcinomas.
Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer.
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
The roles of matrix metalloproteinases-2, -7, -10 and tissue inhibitor of metalloproteinase-1 in the pathogenesis of oral lichen planus.
Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways.
Small interfering RNA-mediated downregulation of beta-catenin inhibits invasion and migration of colon cancer cells in vitro.
The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas.
Matrix metalloproteinase expression in sheep with listerial meningoencephalitis.
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Immunohistochemical expression of matrix metalloproteinases 1, 2, 7, 9, and 26 in the calcifying cystic odontogenic tumor.
Matrix metalloproteinase (MMP)-7 in salivary gland cancer.
E-cadherin, beta-catenin adhesion complex and relation to matrilysin expression in pT3 rectosigmoid cancers.
Potential diagnostic markers in nodular lesions of the thyroid gland: an immunohistochemical study.
Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2.
Role of matrix metalloproteinase-7 in colorectal adenomas.
Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve.
Extracellular matrix metalloproteinase inducer in interstitial pneumonias.
Matrix metalloproteinase induction in fibrosis and fibrotic nodule formation due to silica inhalation.
The multifunctional role of the immunohistochemical expression of MMP-7 in invasive breast cancer.
Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease.
Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease.
Human mevalonate pyrophosphate decarboxylase is localized in the cytosol.
Phosphomevalonate kinase is a cytosolic protein in humans.
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Altadill A, Eiro N, González LO, Andicoechea A, Fernández-Francos S, Rodrigo L, García-Muñiz JL, Vizoso FJ
Biomedicines 2021 Apr 30;9(5)
Biomedicines 2021 Apr 30;9(5)
Expression and Clinical Significance of Metalloproteases and Their Inhibitors by Endothelial Cells From Invasive Breast Carcinomas.
Cid S, Eiro N, González LO, Beridze N, Vazquez J, Vizoso FJ
Clinical breast cancer 2016 Aug;16(4):e83-91
Clinical breast cancer 2016 Aug;16(4):e83-91
Expression of matrix metalloproteinases and their inhibitors in different immunohistochemical-based molecular subtypes of breast cancer.
Kim GE, Lee JS, Choi YD, Lee KH, Lee JH, Nam JH, Choi C, Kim SS, Park MH, Yoon JH, Kweon SS
BMC cancer 2014 Dec 16;14:959
BMC cancer 2014 Dec 16;14:959
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
Suarez-Roa ML, Asbun-Bojalil J, Ruiz-Godoy LM, Meneses-García AA
Australian dental journal 2012 Sep;57(3):300-7
Australian dental journal 2012 Sep;57(3):300-7
The roles of matrix metalloproteinases-2, -7, -10 and tissue inhibitor of metalloproteinase-1 in the pathogenesis of oral lichen planus.
Rubaci AH, Kazancioglu HO, Olgac V, Ak G
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2012 Oct;41(9):689-96
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2012 Oct;41(9):689-96
Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways.
Chang MC, Chen CA, Chen PJ, Chiang YC, Chen YL, Mao TL, Lin HW, Lin Chiang WH, Cheng WF
The Biochemical journal 2012 Mar 1;442(2):293-302
The Biochemical journal 2012 Mar 1;442(2):293-302
Small interfering RNA-mediated downregulation of beta-catenin inhibits invasion and migration of colon cancer cells in vitro.
Han J, Gao B, Jin X, Xu Z, Li Z, Sun Y, Song B
Medical science monitor : international medical journal of experimental and clinical research 2012 Jul;18(7):BR273-80
Medical science monitor : international medical journal of experimental and clinical research 2012 Jul;18(7):BR273-80
The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas.
Li L, Ying J, Li H, Zhang Y, Shu X, Fan Y, Tan J, Cao Y, Tsao SW, Srivastava G, Chan AT, Tao Q
Oncogene 2012 Aug 23;31(34):3901-12
Oncogene 2012 Aug 23;31(34):3901-12
Matrix metalloproteinase expression in sheep with listerial meningoencephalitis.
İlhan F, Ulusoy Y, Halıgür M
Research in veterinary science 2012 Apr;92(2):269-72
Research in veterinary science 2012 Apr;92(2):269-72
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Brun JL, Cortez A, Lesieur B, Uzan S, Rouzier R, Daraï E
Oncology reports 2012 Apr;27(4):1049-57
Oncology reports 2012 Apr;27(4):1049-57
Immunohistochemical expression of matrix metalloproteinases 1, 2, 7, 9, and 26 in the calcifying cystic odontogenic tumor.
Ribeiro BF, Ferreira de Araújo CR, dos Santos BR, de Almeida Freitas R
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011 Nov;112(5):609-15
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2011 Nov;112(5):609-15
Matrix metalloproteinase (MMP)-7 in salivary gland cancer.
Luukkaa H, Klemi P, Hirsimäki P, Vahlberg T, Kivisaari A, Kähäri VM, Grénman R
Acta oncologica (Stockholm, Sweden) 2010;49(1):85-90
Acta oncologica (Stockholm, Sweden) 2010;49(1):85-90
E-cadherin, beta-catenin adhesion complex and relation to matrilysin expression in pT3 rectosigmoid cancers.
Dilek FH, Topak N, Aktepe F, Sahin O, Türel KS, Sahin DA, Dilek ON
Pathology, research and practice 2008;204(11):809-15
Pathology, research and practice 2008;204(11):809-15
Potential diagnostic markers in nodular lesions of the thyroid gland: an immunohistochemical study.
Rydlova M, Ludvikova M, Stankova I
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2008 Jun;152(1):53-9
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2008 Jun;152(1):53-9
Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2.
Brun JL, Cortez A, Commo F, Uzan S, Rouzier R, Daraï E
International journal of oncology 2008 Dec;33(6):1239-46
International journal of oncology 2008 Dec;33(6):1239-46
Role of matrix metalloproteinase-7 in colorectal adenomas.
Kirimlioglu H, Kirimlioglu V, Yilmaz S, Sagir V, Coban S, Turkmen E, Hilmioglu F
Digestive diseases and sciences 2006 Nov;51(11):2068-72
Digestive diseases and sciences 2006 Nov;51(11):2068-72
Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve.
Gantus MA, Nasciutti LE, Cruz CM, Persechini PM, Martinez AM
Brain research 2006 Nov 29;1122(1):36-46
Brain research 2006 Nov 29;1122(1):36-46
Extracellular matrix metalloproteinase inducer in interstitial pneumonias.
Odajima N, Betsuyaku T, Nasuhara Y, Itoh T, Fukuda Y, Senior RM, Nishimura M
Human pathology 2006 Aug;37(8):1058-65
Human pathology 2006 Aug;37(8):1058-65
Matrix metalloproteinase induction in fibrosis and fibrotic nodule formation due to silica inhalation.
Scabilloni JF, Wang L, Antonini JM, Roberts JR, Castranova V, Mercer RR
American journal of physiology. Lung cellular and molecular physiology 2005 Apr;288(4):L709-17
American journal of physiology. Lung cellular and molecular physiology 2005 Apr;288(4):L709-17
The multifunctional role of the immunohistochemical expression of MMP-7 in invasive breast cancer.
Mylona E, Kapranou A, Mavrommatis J, Markaki S, Keramopoulos A, Nakopoulou L
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2005 Apr;113(4):246-55
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2005 Apr;113(4):246-55
Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease.
Kirkegaard T, Hansen A, Bruun E, Brynskov J
Gut 2004 May;53(5):701-9
Gut 2004 May;53(5):701-9
Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease.
Kirkegaard T, Hansen A, Bruun E, Brynskov J
Gut 2004 May;53(5):701-9
Gut 2004 May;53(5):701-9
Human mevalonate pyrophosphate decarboxylase is localized in the cytosol.
Hogenboom S, Tuyp JJ, Espeel M, Koster J, Wanders RJ, Waterham HR
Molecular genetics and metabolism 2004 Mar;81(3):216-24
Molecular genetics and metabolism 2004 Mar;81(3):216-24
Phosphomevalonate kinase is a cytosolic protein in humans.
Hogenboom S, Tuyp JJ, Espeel M, Koster J, Wanders RJ, Waterham HR
Journal of lipid research 2004 Apr;45(4):697-705
Journal of lipid research 2004 Apr;45(4):697-705
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Maguen E, Zorapapel NC, Zieske JD, Ninomiya Y, Sado Y, Kenney MC, Ljubimov AV
Cornea 2002 Jan;21(1):95-100
Cornea 2002 Jan;21(1):95-100
Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK).
Maguen E, Zorapapel NC, Zieske JD, Ninomiya Y, Sado Y, Kenney MC, Ljubimov AV
Cornea 2002 Jan;21(1):95-100
Cornea 2002 Jan;21(1):95-100
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 1 Representative examples of immunohistochemical staining for MMP-7, MMP-14 and TIMP-1 in colonic mucosa of patients depending on the group of study. 100x magnification for ( a - c , g - l , p - r ). 200x magnification for ( d - f , m - o ). The counterstaining was made with hematoxylin. Arrows indicate cell types: red, cancer cells; blue, epithelial cells; green, mononuclear inflammatory cells; and black, fibroblasts. CRC, colorectal cancer; IBD, inflammatory bowel disease. Note: Samples on tissue sections were either insufficient or lost for analysis in 10 cases for MMP-7 in CRCs not associated with IBD; in 5 cases for MMP-14 in CRCs not associated with IBD and in 8 cases of CRCs associated with IBD; in 13 cases for TIMP-1 in CRCs not associated with IBD and in 8 cases of CRCs associated with IBD.
