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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4797 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4797, RRID:AB_1577371
- Product name
- MMP8 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MMP8.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Carboxyterminal cleavage of the chemokines MIG and IP-10 by gelatinase B and neutrophil collagenase.
Neutrophil collagenase (MMP-8) is expressed during early development in neural crest cells as well as in adult melanoma cells.
Matrix metalloproteinases.
Van den Steen PE, Husson SJ, Proost P, Van Damme J, Opdenakker G
Biochemical and biophysical research communications 2003 Oct 24;310(3):889-96
Biochemical and biophysical research communications 2003 Oct 24;310(3):889-96
Neutrophil collagenase (MMP-8) is expressed during early development in neural crest cells as well as in adult melanoma cells.
Giambernardi TA, Sakaguchi AY, Gluhak J, Pavlin D, Troyer DA, Das G, Rodeck U, Klebe RJ
Matrix biology : journal of the International Society for Matrix Biology 2001 Dec;20(8):577-87
Matrix biology : journal of the International Society for Matrix Biology 2001 Dec;20(8):577-87
Matrix metalloproteinases.
Nagase H, Woessner JF Jr
The Journal of biological chemistry 1999 Jul 30;274(31):21491-4
The Journal of biological chemistry 1999 Jul 30;274(31):21491-4
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of MMP8 polyclonal antibody (Cat # PAB4797) in mouse liver tissue lysate (35 ug/lane). MMP8 (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with MMP8 polyclonal antibody (Cat # PAB4797) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
