APR03853G

antibody from Leading Biology

Targeting: MMP8 CLG1

Western blot (Recommended by provider)

Antibody Data

Product number

APR03853G

Provider

Leading Biology

Product name

MMP8 Antibody (N-term)

Antibody type

Polyclonal

Description

Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is stored in secondary granules within neutrophils and isactivated by autolytic cleavage. Its function is degradation oftype I, II and III collagens. The gene is part of a cluster of MMPgenes which localize to chromosome 11q22.3.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.