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Western blot
Immunocytochemistry
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-507-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-507-C100, RRID:AB_2050924
- Product name
- Caspase-11 (mouse) monoclonal antibody (4E11)
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Mouse, Rat
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 4E11
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases.
Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.
van Delft MF, Smith DP, Lahoud MH, Huang DC, Adams JM
Cell death and differentiation 2010 May;17(5):821-32
Cell death and differentiation 2010 May;17(5):821-32
Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.
Marsden VS, Kaufmann T, O'reilly LA, Adams JM, Strasser A
Blood 2006 Mar 1;107(5):1872-7
Blood 2006 Mar 1;107(5):1872-7
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Supportive validation
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- Enzo Life Sciences (provider)
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- Experimental details
- Detection ofendogenous caspase-11 in mouse spleen and lymph node as two bands of 43 and 38 kDa using anti-caspase MAb (4E11). After 16 hours co-culture with LPS 20mg/ml elevated levels of caspase-11 are detected in mouse spleen and lymph node.
