FNab06634

antibody from FineTest Biotech

Targeting: POLR3K C11, RPC11

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: FNab06634 - Provider product page
Provider: FineTest Biotech
Product name: POLR3K antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: polymerase(RNA) III(DNA directed) p olypeptide K, 12.3 kDa
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

POLR3K protein structure - FNab06634 shown in red.