20350-1-AP

antibody from Proteintech Group

Targeting: SLC1A5 AAAT, ASCT2, M7V1, RDRC

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

20350-1-AP

Provider

Proteintech Group

Product name

ASCT2 antibody

Antibody type

Polyclonal

Description

ASCT2 antibody (Cat. #20350-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine.

Shi X, Zhang Y, Wang Y, Wang J, Gao Y, Wang R, Wang L, Xiong M, Cao Y, Ou N, Liu Q, Ma H, Cai J, Chen H
Cell death and differentiation 2024 Sep;31(9):1219-1234

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Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy.

Zhao Y, Liu Z, Deng K, Qu H, Zhang Q, Zhou P, Yang M, Yang X, Wang H, Li R, Xia J
International immunopharmacology 2024 May 10;132:111998

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Characterization of the proteome of stable and unstable carotid atherosclerotic plaques using data-independent acquisition mass spectrometry.

Lai Z, Wang C, Liu X, Sun H, Guo Z, Shao J, Li K, Chen J, Wang J, Lei X, Shu K, Feng Y, Kong D, Sun W, Liu B
Journal of translational medicine 2024 Mar 7;22(1):247

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Progesterone inhibits endometrial cancer growth by inhibiting glutamine metabolism through ASCT2.

Guo J, Fan J, Zhang Y, Li M, Jin Z, Shang Y, Zhang H, Kong Y
Bioscience reports 2024 Mar 29;44(3)

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Baicalein induces apoptosis by inhibiting the glutamine-mTOR metabolic pathway in lung cancer.

Li J, Zhang D, Wang S, Yu P, Sun J, Zhang Y, Meng X, Li J, Xiang L
Journal of advanced research 2024 Mar 2;

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PoRVA G9P[23] and G5P[7] infections differentially promote PEDV replication by reprogramming glutamine metabolism.

Liu H, Tian H, Hao P, Du H, Wang K, Qiu Y, Yin X, Wu N, Du Q, Tong D, Huang Y
PLoS pathogens 2024 Jun;20(6):e1012305

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Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.

Bian Y, Yin G, Wang G, Liu T, Liang L, Yang X, Zhang W, Tang D
Cell biology and toxicology 2023 Oct;39(5):1957-1978

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Therapeutic applications of local injection of hsa-miR-634 into canine spontaneous malignant melanoma tumors.

Yoshikawa R, Inoue J, Iwasaki R, Terauchi M, Fujii Y, Ohta M, Hasegawa T, Mizuno R, Mori T, Inazawa J
Cancer gene therapy 2023 Nov;30(11):1524-1529

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ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells.

Hu Q, Dai J, Zhang Z, Yu H, Zhang J, Zhu X, Qin Y, Zhang L, Zhang P
Cancer research 2023 May 15;83(10):1646-1665

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SLC1A5, unrelated to prognosis, was associated with CD8(+) T-cell exclusion in the tumor microenvironment of squamous cell carcinoma.

Zheng S, Liu T, Li L, Liu Q, Huang C, Liang Y, Tan Y, Zhang L, Lu X
Heliyon 2023 Mar;9(3):e14571

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A pan-cancer analysis of SLC1A5 in human cancers.

Ni J, Dai W, Liu C, Ling Y, Mou H
Heliyon 2023 Jun;9(6):e17598

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Procyanidin B2 3,3″-di-O-gallate suppresses IFN-γ production in murine CD4(+) T cells through the regulation of glutamine influx via direct interaction with ASCT2.

Endo K, Sawa T, Kitamura H, Umezawa K, Makabe H, Tanaka S
International immunopharmacology 2023 Feb;115:109617

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PPAR-γ integrates obesity and adipocyte clock through epigenetic regulation of Bmal1.

Wang S, Lin Y, Gao L, Yang Z, Lin J, Ren S, Li F, Chen J, Wang Z, Dong Z, Sun P, Wu B
Theranostics 2022;12(4):1589-1606

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Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma.

Tran PX, Inoue J, Harada H, Inazawa J
Molecular therapy oncolytics 2022 Mar 17;24:897-908

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HepaCAM‑PIK3CA axis regulates the reprogramming of glutamine metabolism to inhibit prostate cancer cell proliferation.

He Z, Gao Y, Li T, Yu C, Ou L, Luo C
International journal of oncology 2022 Apr;60(4)

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Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment.

Ye D, Xu H, Xia H, Zhang C, Tang Q, Bi F
Journal of experimental & clinical cancer research : CR 2021 May 18;40(1):173

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Augmentation of lenvatinib efficacy by topical treatment of miR-634 ointment in anaplastic thyroid cancer.

Kishikawa M, Inoue J, Hamamoto H, Kobayashi K, Asakage T, Inazawa J
Biochemistry and biophysics reports 2021 Jul;26:101009

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Ferroptosis-related gene signature correlates with the tumor immune features and predicts the prognosis of glioma patients.

Hu Y, Tu Z, Lei K, Huang K, Zhu X
Bioscience reports 2021 Dec 22;41(12)

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The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.

Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, Guan R, Wei X
Aging 2020 Jul 27;12(14):14391-14405

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Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment.

Inoue J, Fujiwara K, Hamamoto H, Kobayashi K, Inazawa J
Molecular therapy oncolytics 2020 Dec 16;19:294-307