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- References [11]
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- Product number
- GTX70141 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70141, RRID:AB_372131
- Product name
- DNA ligase I antibody [10H5]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse
- Host
- Mouse
Submitted references Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA Damage.
Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein.
Interaction between DNA Polymerase β and BRCA1.
Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.
Pol β associated complex and base excision repair factors in mouse fibroblasts.
DNA polymerase beta-dependent long patch base excision repair in living cells.
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
Low levels of DNA ligases III and IV sufficient for effective NHEJ.
A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes.
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex.
DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
Tsai YC, Wang YH, Liu YC
Journal of nucleic acids 2017;2017:8154646
Journal of nucleic acids 2017;2017:8154646
Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein.
Yuan Y, Britton S, Delteil C, Coates J, Jackson SP, Barboule N, Frit P, Calsou P
Nucleic acids research 2015 Dec 2;43(21):10264-76
Nucleic acids research 2015 Dec 2;43(21):10264-76
Interaction between DNA Polymerase β and BRCA1.
Masaoka A, Gassman NR, Horton JK, Kedar PS, Witt KL, Hobbs CA, Kissling GE, Tano K, Asagoshi K, Wilson SH
PloS one 2013;8(6):e66801
PloS one 2013;8(6):e66801
Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.
Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH
DNA repair 2013 Sep;12(9):774-85
DNA repair 2013 Sep;12(9):774-85
Pol β associated complex and base excision repair factors in mouse fibroblasts.
Prasad R, Williams JG, Hou EW, Wilson SH
Nucleic acids research 2012 Dec;40(22):11571-82
Nucleic acids research 2012 Dec;40(22):11571-82
DNA polymerase beta-dependent long patch base excision repair in living cells.
Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH
DNA repair 2010 Feb 4;9(2):109-19
DNA repair 2010 Feb 4;9(2):109-19
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B
Nucleic acids research 2009 Jun;37(10):3431-41
Nucleic acids research 2009 Jun;37(10):3431-41
Low levels of DNA ligases III and IV sufficient for effective NHEJ.
Windhofer F, Wu W, Iliakis G
Journal of cellular physiology 2007 Nov;213(2):475-83
Journal of cellular physiology 2007 Nov;213(2):475-83
A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes.
Song W, Levin DS, Varkey J, Post S, Bermudez VP, Hurwitz J, Tomkinson AE
The Journal of biological chemistry 2007 Aug 3;282(31):22721-30
The Journal of biological chemistry 2007 Aug 3;282(31):22721-30
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex.
Wang W, Lindsey-Boltz LA, Sancar A, Bambara RA
The Journal of biological chemistry 2006 Jul 28;281(30):20865-72
The Journal of biological chemistry 2006 Jul 28;281(30):20865-72
DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, Iliakis G
Cancer research 2005 May 15;65(10):4020-30
Cancer research 2005 May 15;65(10):4020-30
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Supportive validation
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- GeneTex (provider)
- Main image
- Experimental details
- Detection of human Ligase I protein in Raji whole cell lysate using GeneTex DNA Ligase I 10H5 monoclonal antibody GTX70141. Also available in 200ug size GTX70142. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
