10306-1-AP

antibody from Proteintech Group

Targeting: NPM1 B23, NPM

Provider product page for 10306-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [15]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 10306-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10306-1-AP, RRID:AB_2155163
Product name: B23/NPM1 antibody
Antibody type: Polyclonal
Description: B23/NPM1 antibody (Cat. #10306-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

NPM1 protein structure - 10306-1-AP shown in red.

Submitted references Nucleolar Phosphoprotein NPM1 Interacts With Porcine Circovirus Type 3 Cap Protein and Facilitates Viral Replication.

Song J, Hou L, Wang D, Wei L, Zhu S, Wang J, Quan R, Jiang H, Shi R, Liu J
Frontiers in microbiology 2021;12:679341

TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus:Implications for p53 Regulation and Neurite Outgrowth.

Hassan A, Iftinca M, Young D, Flynn R, Agosti F, Abdullah N, Defaye M, Scott MGH, Dufour A, Altier C
International journal of molecular sciences 2021 Feb 25;22(5)

RPL32 Promotes Lung Cancer Progression by Facilitating p53 Degradation.

Xie J, Zhang W, Liang X, Shuai C, Zhou Y, Pan H, Yang Y, Han W
Molecular therapy. Nucleic acids 2020 Sep 4;21:75-85

Nucleolar stress regulates stromal-epithelial transition via NPM1 during decidualization.

Liang YX, Hu W, Jin ZY, Diao HL, Liu L, Yang Y, Fu T, Yang ZM
Reproduction (Cambridge, England) 2020 Oct;160(4):491-500

Triptolide interrupts rRNA synthesis and induces the RPL23‑MDM2‑p53 pathway to repress lung cancer cells.

Wang J, Zhang ZQ, Li FQ, Chen JN, Gong X, Cao BB, Wang W
Oncology reports 2020 Jun;43(6):1863-1874

CircRNA WHSC1 targets the miR-646/NPM1 pathway to promote the development of endometrial cancer.

Liu Y, Chen S, Zong ZH, Guan X, Zhao Y
Journal of cellular and molecular medicine 2020 Jun;24(12):6898-6907

Subcellular localization of the porcine deltacoronavirus nucleocapsid protein.

Ding Z, Luo S, Gong W, Wang L, Ding N, Chen J, Chen J, Wang T, Ye Y, Song D, Kong L, Zhang J, Tang Y
Virus genes 2020 Dec;56(6):687-695

Global profiling of O-GlcNAcylated and/or phosphorylated proteins in hepatoblastoma.

Song H, Ma J, Bian Z, Chen S, Zhu J, Wang J, Huang N, Yin M, Sun F, Xu M, Pan Q
Signal transduction and targeted therapy 2019;4:40

Nucleolar stress regulation of endometrial receptivity in mouse models and human cell lines.

Hu W, Liang YX, Luo JM, Gu XW, Chen ZC, Fu T, Zhu YY, Lin S, Diao HL, Jia B, Yang ZM
Cell death & disease 2019 Nov 4;10(11):831

Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.

Ide M, Ohnishi T, Toyoshima M, Balan S, Maekawa M, Shimamoto-Mitsuyama C, Iwayama Y, Ohba H, Watanabe A, Ishii T, Shibuya N, Kimura Y, Hisano Y, Murata Y, Hara T, Morikawa M, Hashimoto K, Nozaki Y, Toyota T, Wada Y, Tanaka Y, Kato T, Nishi A, Fujisawa S, Okano H, Itokawa M, Hirokawa N, Kunii Y, Kakita A, Yabe H, Iwamoto K, Meno K, Katagiri T, Dean B, Uchida K, Kimura H, Yoshikawa T
EMBO molecular medicine 2019 Dec;11(12):e10695

LNMICC Promotes Nodal Metastasis of Cervical Cancer by Reprogramming Fatty Acid Metabolism.

Shang C, Wang W, Liao Y, Chen Y, Liu T, Du Q, Huang J, Liang Y, Liu J, Zhao Y, Guo L, Hu Z, Yao S
Cancer research 2018 Feb 15;78(4):877-890

High expression of B23 is associated with tumorigenesis and poor prognosis in bladder urothelial carcinoma.

Wang H, Yuan G, Zhao B, Zhao Y, Qiu Y
Molecular medicine reports 2017 Feb;15(2):743-749

Protein expression of nucleophosmin, annexin A3 and nm23-H1 correlates with human nasopharyngeal carcinoma radioresistance in vivo.

Qu S, Li XY, Liang ZG, Li L, Huang ST, Li JQ, Li DR, Zhu XD
Oncology letters 2016 Jul;12(1):615-620

Proteomic characterization of the nucleolar linker histone H1 interaction network.

Szerlong HJ, Herman JA, Krause CM, DeLuca JG, Skoultchi A, Winger QA, Prenni JE, Hansen JC
Journal of molecular biology 2015 Jun 5;427(11):2056-71

Granulocyte colony-stimulating factor improves neuron survival in experimental spinal cord injury by regulating nucleophosmin-1 expression.

Guo Y, Liu S, Wang P, Zhang H, Wang F, Bing L, Gao J, Yang J, Hao A
Journal of neuroscience research 2014 Jun;92(6):751-60

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The B23 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human B23. This antibody recognizes human antigen. The B23 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Appendix: 10306-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 10306-1-AP(NPM1 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 10306-1-AP(NPM1 antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue