APR00454G

antibody from Leading Biology

Targeting: SMC3 BAM, bamacan, CSPG6, HCAP, SMC3L1

No application information provided.

Antibody Data

Product number

APR00454G

Provider

Leading Biology

Product name

Smc3K112/113ac polyclonal antibody

Antibody type

Polyclonal

Description

Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.