BS2765

antibody from Bioworld Technology, Inc

Targeting: HTR1B 5-HT1B, 5-HT1DB, HTR1D2, S12

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

BS2765

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS2765, RRID:AB_1662573

Product name

SR 1B (M305) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 160-210 of Human SR-2C.

Description

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. ÉÇ-adrenergic bound to adrenaline activates adenylyl cyclase, while Ï«2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the Ï«2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories,designated SR-1ÿ7 (5HT1ÿ7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.