ABIN401027

antibody from antibodies-online

Targeting: CCNL1 ania-6a

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN401027

Provider

antibodies-online

Product name

anti-Cyclin L1 (CCNL1) (AA 314-369), (Isoform 1) antibody

Antibody type

Polyclonal

Antigen

Synthetic polypeptide corresponding to amino acids 314-369 of Human Cyclin L1alpha protein

Description

Affinity chromatography on Protein A

Reactivity

Human

Host

Rabbit

Epitope

AA 314-369,Isoform 1

Isotype

IgG

Vial size

0.5 mg

Concentration

5.0 mg/mL (by UV absorbance at 280 nm)

Storage

Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Amplification of Cyclin L1 is associated with lymph node metastases in head and neck squamous cell carcinoma (HNSCC).

Sticht C, Hofele C, Flechtenmacher C, Bosch FX, Freier K, Lichter P, Joos S
British journal of cancer 2005 Feb 28;92(4):770-4

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Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells.

Yang L, Li N, Wang C, Yu Y, Yuan L, Zhang M, Cao X
The Journal of biological chemistry 2004 Mar 19;279(12):11639-48

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Cyclin L is an RS domain protein involved in pre-mRNA splicing.

Dickinson LA, Edgar AJ, Ehley J, Gottesfeld JM
The Journal of biological chemistry 2002 Jul 12;277(28):25465-73

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Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin.

Berke JD, Sgambato V, Zhu PP, Lavoie B, Vincent M, Krause M, Hyman SE
Neuron 2001 Oct 25;32(2):277-87