Ab107031

antibody from Aladdin Scientific Corporation

Targeting: HDAC2 KDAC2, RPD3, YAF1

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab107031

Provider

Aladdin Scientific Corporation

Product name

Recombinant HDAC2 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human HDAC2 Antibody, Recombinant (R06-4E4), could be used for WB, IHC, IF, ICC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100IF/ICC: 1/50-1/200Protein Function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 339-488


Antibody clone number

R06-4E4

Vial size

100μl,10μl,1ml,50μl

Concentration

0,6 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.