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- Antibody Data
- Antigen structure
- References [3]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- NBP1-88512 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-88512, RRID:AB_11010112
- Product name
- Rabbit Polyclonal IBTK Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human IBTK antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis.
The expression of inhibitor of bruton's tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis.
Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response.
Vecchio E, Golino G, Pisano A, Albano F, Falcone C, Ceglia S, Iaccino E, Mimmi S, Fiume G, Giurato G, Britti D, Scala G, Quinto I
Cell death & disease 2019 Apr 11;10(4):320
Cell death & disease 2019 Apr 11;10(4):320
The expression of inhibitor of bruton's tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis.
Albano F, Chiurazzi F, Mimmi S, Vecchio E, Pastore A, Cimmino C, Frieri C, Iaccino E, Pisano A, Golino G, Fiume G, Mallardo M, Scala G, Quinto I
Cell death & disease 2018 Jan 9;9(1):13
Cell death & disease 2018 Jan 9;9(1):13
Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response.
Willy JA, Young SK, Mosley AL, Gawrieh S, Stevens JL, Masuoka HC, Wek RC
The Journal of biological chemistry 2017 Aug 25;292(34):14050-14065
The Journal of biological chemistry 2017 Aug 25;292(34):14050-14065
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: IBTK Antibody [NBP1-88512] - Simple Western lane view shows a specific band for IBTK in 0.2 mg/ml of U-251 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: IBTK Antibody [NBP1-88512] - Electropherogram image(s) of corresponding Simple Western lane view. IBTK antibody was used at 1:20 dilution on U-251 lysate(s).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: IBTK Antibody [NBP1-88512] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
