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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- NB100-416 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-416, RRID:AB_2066307
- Product name
- Rabbit Polyclonal BRIP1/FANCJ Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Fanconi anemia with sun-sensitivity caused by a Xeroderma pigmentosum-associated missense mutation in XPF.
A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy.
Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling.
Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways.
Genotyping of fanconi anemia patients by whole exome sequencing: advantages and challenges.
FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer.
CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice.
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
Popp I, Punekar M, Telford N, Stivaros S, Chandler K, Minnis M, Castleton A, Higham C, Hopewell L, Gareth Evans D, Raams A, Theil AF, Meyer S, Schindler D
BMC medical genetics 2018 Jan 11;19(1):7
BMC medical genetics 2018 Jan 11;19(1):7
A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy.
Bermudez-Hernandez K, Keegan S, Whelan DR, Reid DA, Zagelbaum J, Yin Y, Ma S, Rothenberg E, Fenyö D
Scientific reports 2017 Nov 1;7(1):14882
Scientific reports 2017 Nov 1;7(1):14882
Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling.
Romick-Rosendale LE, Hoskins EE, Privette Vinnedge LM, Foglesong GD, Brusadelli MG, Potter SS, Komurov K, Brugmann SA, Lambert PF, Kimple RJ, Virts EL, Hanenberg H, Gillison ML, Wells SI
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Apr 15;22(8):2062-73
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Apr 15;22(8):2062-73
Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways.
Aarts M, Bajrami I, Herrera-Abreu MT, Elliott R, Brough R, Ashworth A, Lord CJ, Turner NC
Molecular cancer therapeutics 2015 Apr;14(4):865-76
Molecular cancer therapeutics 2015 Apr;14(4):865-76
Genotyping of fanconi anemia patients by whole exome sequencing: advantages and challenges.
Knies K, Schuster B, Ameziane N, Rooimans M, Bettecken T, de Winter J, Schindler D
PloS one 2012;7(12):e52648
PloS one 2012;7(12):e52648
FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer.
Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y, Maehara Y
Annals of surgical oncology 2012 Oct;19(11):3627-35
Annals of surgical oncology 2012 Oct;19(11):3627-35
CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.
Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, Kitao H, Maehara Y
Genes to cells : devoted to molecular & cellular mechanisms 2012 Dec;17(12):962-70
Genes to cells : devoted to molecular & cellular mechanisms 2012 Dec;17(12):962-70
Mutation of the RAD51C gene in a Fanconi anemia-like disorder.
Vaz F, Hanenberg H, Schuster B, Barker K, Wiek C, Erven V, Neveling K, Endt D, Kesterton I, Autore F, Fraternali F, Freund M, Hartmann L, Grimwade D, Roberts RG, Schaal H, Mohammed S, Rahman N, Schindler D, Mathew CG
Nature genetics 2010 May;42(5):406-9
Nature genetics 2010 May;42(5):406-9
Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice.
Duan SZ, Ivashchenko CY, Russell MW, Milstone DS, Mortensen RM
Circulation research 2005 Aug 19;97(4):372-9
Circulation research 2005 Aug 19;97(4):372-9
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM
Cell 2001 Apr 6;105(1):149-60
Cell 2001 Apr 6;105(1):149-60
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM
Cell 2001 Apr 6;105(1):149-60
Cell 2001 Apr 6;105(1):149-60
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: BRIP1/FANCJ Antibody [NB100-416] - Used to detect BRIP1/FANCJ in cell lysates. Lane 1: MCF-7 lysate, Lane 2: HeLa lysate, Lane 3: 293 lysate and Lane 4: SKOV3 lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: BRIP1/FANCJ Antibody [NB100-416] - Analysis on MCF7, HeLa, 293T and SKOV3 crude cell lysates.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: BRIP1/FANCJ Antibody [NB100-416] - Analysis in human colon and rectum tissues. Image courtesy of an anonymous customer review.
