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- References [10]
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- Product number
- ABIN445494 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ligase III, DNA, ATP-Dependent (LIG3) antibody
- Antibody type
- Monoclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Chicken/Avian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 1F3
- Vial size
- 100 μL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Arsenicals affect base excision repair by several mechanisms.
Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors.
DNA polymerase beta-dependent long patch base excision repair in living cells.
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair.
Low levels of DNA ligases III and IV sufficient for effective NHEJ.
ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha.
Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells.
DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair.
Ebert F, Weiss A, Bültemeyer M, Hamann I, Hartwig A, Schwerdtle T
Mutation research 2011 Oct 1;715(1-2):32-41
Mutation research 2011 Oct 1;715(1-2):32-41
Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors.
Singh SK, Wu W, Zhang L, Klammer H, Wang M, Iliakis G
International journal of radiation oncology, biology, physics 2011 Feb 1;79(2):540-8
International journal of radiation oncology, biology, physics 2011 Feb 1;79(2):540-8
DNA polymerase beta-dependent long patch base excision repair in living cells.
Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH
DNA repair 2010 Feb 4;9(2):109-19
DNA repair 2010 Feb 4;9(2):109-19
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B
Nucleic acids research 2009 Jun;37(10):3431-41
Nucleic acids research 2009 Jun;37(10):3431-41
Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair.
Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell AD Jr, Tomkinson AE
Cancer research 2008 May 1;68(9):3169-77
Cancer research 2008 May 1;68(9):3169-77
Low levels of DNA ligases III and IV sufficient for effective NHEJ.
Windhofer F, Wu W, Iliakis G
Journal of cellular physiology 2007 Nov;213(2):475-83
Journal of cellular physiology 2007 Nov;213(2):475-83
ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha.
Dong Z, Tomkinson AE
Nucleic acids research 2006;34(20):5721-279
Nucleic acids research 2006;34(20):5721-279
Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells.
Okano S, Lan L, Tomkinson AE, Yasui A
Nucleic acids research 2005;33(1):422-9
Nucleic acids research 2005;33(1):422-9
DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, Iliakis G
Cancer research 2005 May 15;65(10):4020-30
Cancer research 2005 May 15;65(10):4020-30
Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair.
Leppard JB, Dong Z, Mackey ZB, Tomkinson AE
Molecular and cellular biology 2003 Aug;23(16):5919-27
Molecular and cellular biology 2003 Aug;23(16):5919-27
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- Submitted by
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- Submitted by
- antibodies-online (provider)
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