ARHGEF4

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]

Description

Rho guanine nucleotide exchange factor 4

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

2:q21.1 (130836916 - 131047263)

Ensembl ID

ENSG00000136002  (ver. 99.38)

Orthologs

Mouse Arhgef4: ENSMUSG00000037509

UniProt

Q9NR80

neXtProt

NX_Q9NR80

Human splice variants
Mouse splice variants