FNab00562

antibody from FineTest Biotech

Targeting: ARHGEF4 ASEF, KIAA1112, STM6

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab00562 - Provider product page
Provider: FineTest Biotech
Product name: ARHGEF4 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: Rho guanine nucleotide exchange fac tor(GEF) 4
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ARHGEF4 protein structure - FNab00562 shown in red.