BS8144

antibody from Bioworld Technology, Inc
Targeting: PCGF1 MGC10882, NSPC1, RNF68
Provider product page for BS8144
Western blot
Immunohistochemistry

Antibody data

Product number
BS8144 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PCGF1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PCGF1.
Description
Polycomb group (PCG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several PCG proteins contain ring finger domains and have been identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF1 (polycomb group ring finger 1), also known as NSPC1, RNF68 or RNF3A-2, is a 259 amino acid nuclear protein that is ubiquitously expressed. PCGF1 is a component of the PCG multiprotein BCoR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as Bcl-6 and the cyclin-dependent kinase inhibitor, p21. PCGF1 promotes cell cycle progression and enhances cell proliferation.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PCGF1 protein structure - BS8144 shown in red.