MB0012

antibody from Bioworld Technology, Inc
Targeting: KIF11 Eg5, HKSP, KNSL1, TRIP5
Provider product page for MB0012
Western blot
Immunoprecipitation

Antibody data

Product number
MB0012 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Eg5 / KIF11 monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human Eg5.
Description
Eg5 (also known as Kinesin-like protein KIF11 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of Eg5 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. Eg5 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). Eg5 is also known to be a member of the thyroid receptor interacting protein (TRIP) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KIF11 protein structure - MB0012 shown in red.