627801

antibody from BioLegend
Targeting: KIF11 Eg5, HKSP, KNSL1, TRIP5
Provider product page for 627801
Western blot
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
627801 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#627801, RRID:AB_2130964
Product name
Purified anti-Eg5
Antibody type
Monoclonal
Antigen
Amino Acid: 200-500 of human Eg5
Description
Eg5 (also known as kinesin-like protein KIF11, kinesin-related motor protein Eg5, kinesin-like spindle protein HKSP, and thyroid receptor interacting protein 5 (TRIP5)) is a 119 kD kinesin-like protein family, BimC subfamily. This protein is a catalytic kinesin motor with coiled-coil and Smc domains. Eg5 is localized at the centrosomes, spindle microtubules, and intracellular bridge. This motor protein is required for establishing the bipolar spindle. hEg5 is modified by phosphorylation on Thr927 by Cdc2 to allow association with the spindle apparatus. Eg5 has been shown to interact with the thyroid hormone receptor in presence of thyroid hormone and Cdc2. The 10C7/Eg5 monoclonal antibody has been shown to react with human and mouse Eg5 by Western blot.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C.
KIF11 protein structure - 627801 shown in red.