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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500597 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ras Homolog Enriched in Brain (RHEB) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- Rheb antibody was raised against a 15 amino acid peptide from the middle region of human Rheb.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Rheb is an essential regulator of S6K in controlling cell growth in Drosophila.
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
Stocker H, Radimerski T, Schindelholz B, Wittwer F, Belawat P, Daram P, Breuer S, Thomas G, Hafen E
Nature cell biology 2003 Jun;5(6):559-65
Nature cell biology 2003 Jun;5(6):559-65
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Inoki K, Li Y, Xu T, Guan KL
Genes & development 2003 Aug 1;17(15):1829-34
Genes & development 2003 Aug 1;17(15):1829-34
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
Yee WM, Worley PF
Molecular and cellular biology 1997 Feb;17(2):921-33
Molecular and cellular biology 1997 Feb;17(2):921-33
rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
Yamagata K, Sanders LK, Kaufmann WE, Yee W, Barnes CA, Nathans D, Worley PF
The Journal of biological chemistry 1994 Jun 10;269(23):16333-9
The Journal of biological chemistry 1994 Jun 10;269(23):16333-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Rheb in mouse brain cell lysate with AP30721PU-N at (A) 1, (B) 2, and (C) 4 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of Rheb in mouse brain tissue with AP30721PU-N at 2 ?g/ml.
