Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14768-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14768-1-AP, RRID:AB_2102780
- Product name
- FEN1 antibody
- Antibody type
- Polyclonal
- Description
- FEN1 antibody (Cat. #14768-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma.
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells.
Zhang Y, Liu X, Liu L, Chen J, Hu Q, Shen S, Zhou Y, Chen S, Xue C, Cui G, Yu Z
Disease markers 2020;2020:2514090
Disease markers 2020;2020:2514090
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
Shi R, Wang Y, Gao Y, Xu X, Mao S, Xiao Y, Song S, Wang L, Tian B, Zhao Y, Hua Y, Xu H
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C657-C666
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C657-C666
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, Zhao Y, Tian B, Truong K, Chen Y, Shen B, Hua Y, Xu H
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells.
He L, Yang H, Zhou S, Zhu H, Mao H, Ma Z, Wu T, Kumar AK, Kathera C, Janardhan A, Pan F, Hu Z, Yang Y, Luo L, Guo Z
DNA repair 2018 Mar;63:1-9
DNA repair 2018 Mar;63:1-9
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The FEN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FEN1. This antibody recognizes human, mouse, rat antigen. The FEN1 antibody has been validated for the following applications: ELISA, WB analysis.