Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14768-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14768-1-AP, RRID:AB_2102780
- Product name
- FEN1 antibody
- Antibody type
- Polyclonal
- Description
- FEN1 antibody (Cat. #14768-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Harmine inhibits pulmonary fibrosis through regulating DNA damage repair-related genes and activation of TP53-Gadd45α pathway.
DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1.
CJ(2): A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS.
HIV-1 exploits the Fanconi anemia pathway for viral DNA integration.
Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma.
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells.
Gong Y, Wang J, Pan M, Zhao Y, Zhang H, Zhang F, Liu J, Yang J, Hu J
International immunopharmacology 2024 Sep 10;138:112542
International immunopharmacology 2024 Sep 10;138:112542
DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1.
Chen S, Zhang W, Li X, Cao Z, Liu C
Cell death & disease 2024 Jan 20;15(1):78
Cell death & disease 2024 Jan 20;15(1):78
CJ(2): A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G
Journal of medicinal chemistry 2023 Jan 12;66(1):875-889
Journal of medicinal chemistry 2023 Jan 12;66(1):875-889
Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS.
Wang S, Chen S, Li H, Ben S, Zhao T, Zheng R, Wang M, Gu D, Liu L
Journal of biomedical research 2023 Dec 18;38(1):37-50
Journal of biomedical research 2023 Dec 18;38(1):37-50
HIV-1 exploits the Fanconi anemia pathway for viral DNA integration.
Fu S, Phan AT, Mao D, Wang X, Gao G, Goff SP, Zhu Y
Cell reports 2022 May 24;39(8):110840
Cell reports 2022 May 24;39(8):110840
Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration.
Jhanji M, Rao CN, Massey JC, Hope MC 3rd, Zhou X, Keene CD, Ma T, Wyatt MD, Stewart JA, Sajish M
Nature communications 2022 Jun 10;13(1):3244
Nature communications 2022 Jun 10;13(1):3244
In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome.
Gourdomichali O, Zonke K, Kattan FG, Makridakis M, Kontostathi G, Vlahou A, Doxakis E
Biology 2022 Feb 11;11(2)
Biology 2022 Feb 11;11(2)
Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma.
Zhang Y, Liu X, Liu L, Chen J, Hu Q, Shen S, Zhou Y, Chen S, Xue C, Cui G, Yu Z
Disease markers 2020;2020:2514090
Disease markers 2020;2020:2514090
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability.
Shi R, Wang Y, Gao Y, Xu X, Mao S, Xiao Y, Song S, Wang L, Tian B, Zhao Y, Hua Y, Xu H
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C657-C666
American journal of physiology. Cell physiology 2020 Oct 1;319(4):C657-C666
SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress.
Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, Zhao Y, Tian B, Truong K, Chen Y, Shen B, Hua Y, Xu H
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Journal of molecular cell biology 2018 Oct 1;10(5):460-474
Synergistic antitumor effect of combined paclitaxel with FEN1 inhibitor in cervical cancer cells.
He L, Yang H, Zhou S, Zhu H, Mao H, Ma Z, Wu T, Kumar AK, Kathera C, Janardhan A, Pan F, Hu Z, Yang Y, Luo L, Guo Z
DNA repair 2018 Mar;63:1-9
DNA repair 2018 Mar;63:1-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FEN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FEN1. This antibody recognizes human, mouse, rat antigen. The FEN1 antibody has been validated for the following applications: ELISA, WB analysis.