Antibody data
- Antibody Data
- Antigen structure
- References [42]
- Comments [0]
- Validations [0]
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- Product number
- 14026-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ZEB2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZEB2 antibody (Cat. #14026-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.
LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process.
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
CircRNA Lrp6 promotes cementoblast differentiation via miR-145a-5p/Zeb2 axis.
SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α.
Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Knockdown of Linc00511 inhibits TGF-β-induced cell migration and invasion by suppressing epithelial-mesenchymal transition and down-regulating MMPs expression.
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.
Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.
The Lnc LINC00461/miR-30a-5p facilitates progression and malignancy in non-small cell lung cancer via regulating ZEB2.
Circular RNA hsa_circ_0000326 acts as a miR-338-3p sponge to facilitate lung adenocarcinoma progression.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation.
LncRNA SNHG5 Promotes Proliferation of Glioma by Regulating miR-205-5p/ZEB2 Axis.
MicroRNA-507 represses the malignant behaviors of non-small cell lung cancer via targeting zinc finger E-box binding homeobox 2.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma.
Zinc finger E‑box binding homeobox 2 functions as an oncogene in human laryngeal squamous cell carcinoma.
Long noncoding RNA MAGI1-IT1 promoted invasion and metastasis of epithelial ovarian cancer via the miR-200a/ZEB axis.
Schisandrin B attenuates renal fibrosis via miR-30e-mediated inhibition of EMT.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition.
Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.
High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer.
Lee HY, Li CC, Li WM, Hsu YL, Yeh HC, Ke HL, Yeh BW, Huang CN, Li CF, Kuo PL, Wu WJ
PeerJ 2021;9:e11343
PeerJ 2021;9:e11343
LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process.
Sun Z, Shao B, Liu Z, Dang Q, Guo Y, Chen C, Guo Y, Chen Z, Liu J, Hu S, Yuan W, Zhou Q
Journal of Cancer 2021;12(9):2723-2734
Journal of Cancer 2021;12(9):2723-2734
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Li R, Zhu L, Peng Y, Zhang X, Dai C, Liu D
Frontiers in oncology 2021;11:695740
Frontiers in oncology 2021;11:695740
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29
Nano convergence 2021 Oct 4;8(1):29
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.
Du Y, Liu X, Zhang S, Chen S, Guan X, Li Q, Chen X, Zhao Y
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
Harn HI, Wang SP, Lai YC, Van Handel B, Liang YC, Tsai S, Schiessl IM, Sarkar A, Xi H, Hughes M, Kaemmer S, Tang MJ, Peti-Peterdi J, Pyle AD, Woolley TE, Evseenko D, Jiang TX, Chuong CM
Nature communications 2021 May 10;12(1):2595
Nature communications 2021 May 10;12(1):2595
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Liu C, Zhou X, Pan Y, Liu Y, Zhang Y
BMC cancer 2021 Jun 22;21(1):722
BMC cancer 2021 Jun 22;21(1):722
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
CircRNA Lrp6 promotes cementoblast differentiation via miR-145a-5p/Zeb2 axis.
Li M, Du M, Wang Y, Zhu J, Pan J, Cao Z, He H
Journal of periodontal research 2021 Dec;56(6):1200-1212
Journal of periodontal research 2021 Dec;56(6):1200-1212
SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α.
Cui X, Wang Y, Lan W, Wang S, Cui Y, Zhang X, Lin Z, Piao J
Cellular oncology (Dordrecht) 2021 Dec 2;
Cellular oncology (Dordrecht) 2021 Dec 2;
Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly.
Tsukamoto H, Kouwaki T, Oshiumi H
iScience 2020 Sep 1;23(9):101520
iScience 2020 Sep 1;23(9):101520
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
Knockdown of Linc00511 inhibits TGF-β-induced cell migration and invasion by suppressing epithelial-mesenchymal transition and down-regulating MMPs expression.
Jiang L, Xie X, Bi R, Ding F, Mei J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109049
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109049
Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.
Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399
Cell death & disease 2020 May 26;11(5):399
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Hu Y, Yu J, Wang Q, Zhang L, Chen X, Cao Y, Zhao J, Xu Y, Jiang D, Wang Y, Xiong W
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Liu J, Chen Y, Cao Z, Guan B, Peng J, Chen Y, Zhan Z, Sferra TJ, Sankararaman S, Lin J
The Journal of international medical research 2020 Jun;48(6):300060520925598
The Journal of international medical research 2020 Jun;48(6):300060520925598
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
Wang H, Wang C, Peng G, Yu D, Cui XG, Sun YH, Ma X
Molecular cancer research : MCR 2020 Feb;18(2):240-252
Molecular cancer research : MCR 2020 Feb;18(2):240-252
KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2.
Sun L, Zhou X, Li Y, Chen W, Wu S, Zhang B, Yao J, Xu A
Cell adhesion & migration 2020 Dec;14(1):182-194
Cell adhesion & migration 2020 Dec;14(1):182-194
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.
Ma T, Liang Y, Li Y, Song X, Zhang N, Li X, Chen B, Zhao W, Wang L, Yang Q
Cellular signalling 2020 Apr;68:109536
Cellular signalling 2020 Apr;68:109536
Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.
Wang L, Zhang X, Liu Y, Xu S
Journal of cellular physiology 2020 Apr;235(4):3612-3625
Journal of cellular physiology 2020 Apr;235(4):3612-3625
The Lnc LINC00461/miR-30a-5p facilitates progression and malignancy in non-small cell lung cancer via regulating ZEB2.
Li X, Liu J, Liu M, Xia C, Zhao Q
Cell cycle (Georgetown, Tex.) 2020 Apr;19(7):825-836
Cell cycle (Georgetown, Tex.) 2020 Apr;19(7):825-836
Circular RNA hsa_circ_0000326 acts as a miR-338-3p sponge to facilitate lung adenocarcinoma progression.
Xu Y, Yu J, Huang Z, Fu B, Tao Y, Qi X, Mou Y, Hu Y, Wang Y, Cao Y, Jiang D, Xie J, Xu Y, Zhao J, Xiong W
Journal of experimental & clinical cancer research : CR 2020 Apr 5;39(1):57
Journal of experimental & clinical cancer research : CR 2020 Apr 5;39(1):57
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation.
Wang T, Lin F, Sun X, Jiang L, Mao R, Zhou S, Shang W, Bi R, Lu F, Li S
Cancer cell international 2019;19:3
Cancer cell international 2019;19:3
LncRNA SNHG5 Promotes Proliferation of Glioma by Regulating miR-205-5p/ZEB2 Axis.
Meng X, Deng Y, Lv Z, Liu C, Guo Z, Li Y, Liu H, Xie B, Jin Z, Lin F, Zhu H
OncoTargets and therapy 2019;12:11487-11496
OncoTargets and therapy 2019;12:11487-11496
MicroRNA-507 represses the malignant behaviors of non-small cell lung cancer via targeting zinc finger E-box binding homeobox 2.
Lv HL, Li ZL, Song YB
European review for medical and pharmacological sciences 2019 Nov;23(22):9955-9964
European review for medical and pharmacological sciences 2019 Nov;23(22):9955-9964
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma.
Diao P, Ge H, Song Y, Wu Y, Li J, Li Z, Yang J, Wang Y, Cheng J
Journal of cellular and molecular medicine 2019 Jun;23(6):4269-4280
Journal of cellular and molecular medicine 2019 Jun;23(6):4269-4280
Zinc finger E‑box binding homeobox 2 functions as an oncogene in human laryngeal squamous cell carcinoma.
Li Q, Ma L, Wu Z, Wang G, Huang Q, Shen Z, Yu R
Molecular medicine reports 2019 Jun;19(6):4545-4552
Molecular medicine reports 2019 Jun;19(6):4545-4552
Long noncoding RNA MAGI1-IT1 promoted invasion and metastasis of epithelial ovarian cancer via the miR-200a/ZEB axis.
Gao H, Li X, Zhan G, Zhu Y, Yu J, Wang J, Li L, Wu W, Liu N, Guo X
Cell cycle (Georgetown, Tex.) 2019 Jun;18(12):1393-1406
Cell cycle (Georgetown, Tex.) 2019 Jun;18(12):1393-1406
Schisandrin B attenuates renal fibrosis via miR-30e-mediated inhibition of EMT.
Cao G, Li S, Shi H, Yin P, Chen J, Li H, Zhong Y, Diao LT, Du B
Toxicology and applied pharmacology 2019 Dec 15;385:114769
Toxicology and applied pharmacology 2019 Dec 15;385:114769
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Wu X, Tao P, Zhou Q, Li J, Yu Z, Wang X, Li J, Li C, Yan M, Zhu Z, Liu B, Su L
Oncotarget 2017 Mar 28;8(13):20741-20750
Oncotarget 2017 Mar 28;8(13):20741-20750
miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition.
Yang J, Zhou CZ, Zhu R, Fan H, Liu XX, Duan XY, Tang Q, Shou ZX, Zuo DM
Journal of gastroenterology and hepatology 2017 Dec;32(12):1966-1974
Journal of gastroenterology and hepatology 2017 Dec;32(12):1966-1974
Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.
Zhang S, Li J, Liu P, Xu J, Zhao W, Xie C, Yin Z, Wang X
Oncotarget 2015 May 10;6(13):11074-86
Oncotarget 2015 May 10;6(13):11074-86
High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer.
Qu Y, Ray PS, Li J, Cai Q, Bagaria SP, Moran C, Sim MS, Zhang J, Turner RR, Zhu Z, Cui X, Liu B
European journal of cancer (Oxford, England : 1990) 2013 Nov;49(17):3718-28
European journal of cancer (Oxford, England : 1990) 2013 Nov;49(17):3718-28
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