BS6967

antibody from Bioworld Technology, Inc
Targeting: ACVR2A ACTRII, ACVR2
Provider product page for BS6967
Western blot
Immunohistochemistry

Antibody data

Product number
BS6967 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ACTR IIA polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ACTR-IIA.
Description
Members of the transforming growth factor ÉÇ superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTR-IIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ACVR2A protein structure - BS6967 shown in red.