DCABY12515

antibody from Creative Diagnostics

Targeting: ACVR2A ACTRII, ACVR2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DCABY12515

Provider

Creative Diagnostics

Product name

Anti ACVR2A(N-Terminus) polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at -20°C. Avoid freeze/thaw cycles.