abx001614

antibody from Abbexa

Targeting: ACVR2A ACTRII, ACVR2

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx001614

Provider

Abbexa

Product name

Activin A Receptor Type 2A (ACVR2A) Antibody

Antibody type

Polyclonal

Description

ACVR2A Antibody is a Rabbit Polyclonal antibody against ACVR2A. This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1.81 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.