Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
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- Product number
- ABIN394877 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3) (AA 671-758) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Epitope
- AA 671-758
- Isotype
- IgG
- Antibody clone number
- 1C1
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references KCNC3: phenotype, mutations, channel biophysics-a study of 260 familial ataxia patients.
Sca13.
Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes.
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.
Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.
Figueroa KP, Minassian NA, Stevanin G, Waters M, Garibyan V, Forlani S, Strzelczyk A, Bürk K, Brice A, Dürr A, Papazian DM, Pulst SM
Human mutation 2010 Feb;31(2):191-6
Human mutation 2010 Feb;31(2):191-6
Sca13.
Waters MF, Pulst SM
Cerebellum (London, England) 2008;7(2):165-9
Cerebellum (London, England) 2008;7(2):165-9
Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes.
Waters MF, Minassian NA, Stevanin G, Figueroa KP, Bannister JP, Nolte D, Mock AF, Evidente VG, Fee DB, Müller U, Dürr A, Brice A, Papazian DM, Pulst SM
Nature genetics 2006 Apr;38(4):447-51
Nature genetics 2006 Apr;38(4):447-51
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X
Pharmacological reviews 2005 Dec;57(4):473-508
Pharmacological reviews 2005 Dec;57(4):473-508
Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.
Brusco A, Gellera C, Cagnoli C, Saluto A, Castucci A, Michielotto C, Fetoni V, Mariotti C, Migone N, Di Donato S, Taroni F
Archives of neurology 2004 May;61(5):727-33
Archives of neurology 2004 May;61(5):727-33
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB