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- Western blot [1]
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- Product number
- GTX16196 - Provider product page
- Provider
- GeneTex
- Product name
- RAB7A antibody [Rab7-117]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Simian
- Host
- Mouse
Submitted references Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
C9orf72 is required for proper macrophage and microglial function in mice.
Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK
Nature medicine 2018 Mar;24(3):313-325
Nature medicine 2018 Mar;24(3):313-325
C9orf72 is required for proper macrophage and microglial function in mice.
O'Rourke JG, Bogdanik L, Yáñez A, Lall D, Wolf AJ, Muhammad AK, Ho R, Carmona S, Vit JP, Zarrow J, Kim KJ, Bell S, Harms MB, Miller TM, Dangler CA, Underhill DM, Goodridge HS, Lutz CM, Baloh RH
Science (New York, N.Y.) 2016 Mar 18;351(6279):1324-9
Science (New York, N.Y.) 2016 Mar 18;351(6279):1324-9
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Cell line lysates were separated on SDS-PAGE and probed with1 μg/mL Monoclonal Anti-Rab7 Clone: Rab7-117 (GTX16196). Lanes1. HeLa; 2. HepG2; 3. NRK; 4. 3T3; 5. MDCK
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- HeLa cells were fixed and permeabilized with 4% paraformaldehyde followed by 0.5% saponin. Fixed cells were stained with 10 μg/mL Monoclonal Anti-Rab7 Clone: Rab7-117 (GTX16196). The antibody was developed using Goat Anti-Mouse IgG, Atto-488 conjμgate.
