BS8934

antibody from Bioworld Technology, Inc
Targeting: SAR1A SAR1, Sara, SARA1
Provider product page for BS8934
Western blot
Immunohistochemistry

Antibody data

Product number
BS8934 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SAR1A polyclonal antibody
Antibody type
Polyclonal
Antigen
GTP-binding protein SAR1a; COPII-associated small GTPase; SAR1A; SAR1, SARA, SARA1
Description
There are a number of components involved in the secretory pathway of cells. Vesicular traffic within the early secretory pathway is mediated by COPI- and COPII-coated vesicles. The COPII vesicle coat protein promotes the formation of endoplasmic reticulum (ER) derived transport vesicles that carry secretory proteins to the Golgi complex. The SAR1 gene encodes two isoforms, Sar1a and Sar1B, in mammalian cells. These proteins are low-molecular-weight GTPases, which are essential for the formation of transport vesicles from the ER. Mutations in the SAR1 gene result in Anderson£ªs disease (and/or chylomicron retention disease CMRD), a rare, autosomal recessive lipid malabsorption disorder characterized by chronic diarrhea, failure to thrive and hypocholesterolemia in childhood.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SAR1A protein structure - BS8934 shown in red.