Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11-12016-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-POU3F2 Antibody
- Antibody type
- Polyclonal
- Description
- POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in post-mitotic neurons and glia.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant POU3F2
protein (amino acids 220-421) was
used as the immunogen for this anti
body.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
No comments: Submit comment
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Expression analysis of POU3F2. Anti-POU3F2 antibody (11-12016) was used at 1 µg/ml on (1) K562, (2) HCT-116 and (3) 293 lysates