Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 15287-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15287-1-AP, RRID:AB_2248640
- Product name
- HSPB8 antibody
- Antibody type
- Polyclonal
- Description
- HSPB8 antibody (Cat. #15287-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
The α crystallin domain of small heat shock protein b8 (Hspb8) acts as survival and differentiation factor in adult hippocampal neurogenesis.
Martin TG, Delligatti CE, Muntu NA, Stachowski-Doll MJ, Kirk JA
Journal of cellular biochemistry 2021 Sep 6;
Journal of cellular biochemistry 2021 Sep 6;
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Martin TG, Myers VD, Dubey P, Dubey S, Perez E, Moravec CS, Willis MS, Feldman AM, Kirk JA
Nature communications 2021 May 19;12(1):2942
Nature communications 2021 May 19;12(1):2942
The α crystallin domain of small heat shock protein b8 (Hspb8) acts as survival and differentiation factor in adult hippocampal neurogenesis.
Ramírez-Rodríguez G, Babu H, Klempin F, Krylyshkina O, Baekelandt V, Gijsbers R, Debyser Z, Overall RW, Nicola Z, Fabel K, Kempermann G
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Mar 27;33(13):5785-96
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Mar 27;33(13):5785-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 15287-1-AP(HSPB8 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 15287-1-AP(HSPB8 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSPB8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSPB8. This antibody recognizes human, mouse, rat antigen. The HSPB8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.