BS7723

antibody from Bioworld Technology, Inc
Targeting: HSPB8 CMT2L, E2IG1, H11, HSP22
Provider product page for BS7723
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7723 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HSPB8 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HSPB8.
Description
?Crystallins are the major proteins expressed in the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into a, b and g families; b and g-crystallins compose a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. a-crystallins consist of three gene products, aA, aB and aC-crystallin, which are members of the small heat shock protein family (HSP20). They are induced by heat shock, and act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, a-crystallins do not renature these proteins. Research indicates that binding occurs between membranes and aC-crystallin. The binding site appears to be at the polar-apolar interface in membrane protein (MIP26) and aC-crystallin; the lipid bilayer becomes less mobile with aC-crystallin binding.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HSPB8 protein structure - BS7723 shown in red.