BS7475

antibody from Bioworld Technology, Inc
Targeting: ABCC5 EST277145, MOAT-C, MRP5, SMRP
Provider product page for BS7475
Western blot
Immunohistochemistry

Antibody data

Product number
BS7475 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ABCC5 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ABCC5.
Description
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ABCC5 protein structure - BS7475 shown in red.