Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11-8007-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-CLIM1/PDLIM1 Antibody
- Antibody type
- Polyclonal
- Description
- PDLIM1 (PDZ and LIM Domain 1) belongs to the enigma protein family. It contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxy terminal. LIM domains are cysteine-rich double zinc fingers that are involved in protein-protein interactions. PDLIM1 has transcription coactivatior activity and it may play a role as an adapter to bring other LIM-interacting proteins to the cytoskeleton. This gene is found to be highly expressed in the heart and skeletal muscle and moderately expressed in the spleen. PDLIM1 consists of 329 amino acids and is associated with hyperacusis and supravalvular aortic stenosis diseases.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant CLIM1
protein (amino acids 116-329) was u
sed as the immunogen for this antib
ody.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of CLIM1. Anti- CLIM1 antibody (11-8007) was used at 1 µg/ml on 1) Heart, 2) SKM and 3) HepG2 lysates.
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of CLIM1. Anti-CLIM1 antibody (11-8007) in human Colon tissue at 5 µg/ml.