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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6531 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- B2M polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human B2M.
- Description
- Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an a heavy chain that contains three subdomains (Ï«1, Ï«2, Ï«3), and a non-covalent associating light chain, known as ÉÇ-2-Microglobulin. ÉÇ-2-Microglobulin associates with the a3 subdomain of the a heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The Ï«1 and Ï«2 domains of the a heavy chain form the peptide antigen-binding cleft.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of extracts of various cell lines, using B2M antibody.
