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Immunocytochemistry
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Other assay [1]
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- Product number
- V2802 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Beta-2 Microglobulin Antibody
- Antibody type
- Monoclonal
- Antigen
- MOLT-4 human T cell line was used as the immunogen for the Beta-2 Microglobulin antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- BBM.1
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Beta-2 Microglobulin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Regulation and trafficking of the HLA-E molecules during monocyte-macrophage differentiation.
Dissociation of β2-microglobulin determines the surface quality control of major histocompatibility complex class I molecules.
Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.
WEE1 inhibition alleviates resistance to immune attack of tumor cells undergoing epithelial-mesenchymal transition.
The biochemistry and immunology of non-canonical forms of HLA-B27.
Genetic evolution of T-cell resistance in the course of melanoma progression.
MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro.
Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells.
MR1B, a natural spliced isoform of the MHC-related 1 protein, is expressed as homodimers at the cell surface and activates MAIT cells.
HLA engineering of human pluripotent stem cells.
Activation of complement by monoclonal antibodies that target cell-associated β₂-microglobulin: implications for cancer immunotherapy.
Camilli G, Cassotta A, Battella S, Palmieri G, Santoni A, Paladini F, Fiorillo MT, Sorrentino R
Journal of leukocyte biology 2016 Jan;99(1):121-30
Journal of leukocyte biology 2016 Jan;99(1):121-30
Dissociation of β2-microglobulin determines the surface quality control of major histocompatibility complex class I molecules.
Montealegre S, Venugopalan V, Fritzsche S, Kulicke C, Hein Z, Springer S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Jul;29(7):2780-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Jul;29(7):2780-8
Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.
Apps R, Meng Z, Del Prete GQ, Lifson JD, Zhou M, Carrington M
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3594-600
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3594-600
WEE1 inhibition alleviates resistance to immune attack of tumor cells undergoing epithelial-mesenchymal transition.
Hamilton DH, Huang B, Fernando RI, Tsang KY, Palena C
Cancer research 2014 May 1;74(9):2510-9
Cancer research 2014 May 1;74(9):2510-9
The biochemistry and immunology of non-canonical forms of HLA-B27.
Shaw J, Hatano H, Kollnberger S
Molecular immunology 2014 Jan;57(1):52-8
Molecular immunology 2014 Jan;57(1):52-8
Genetic evolution of T-cell resistance in the course of melanoma progression.
Sucker A, Zhao F, Real B, Heeke C, Bielefeld N, Maβen S, Horn S, Moll I, Maltaner R, Horn PA, Schilling B, Sabbatino F, Lennerz V, Kloor M, Ferrone S, Schadendorf D, Falk CS, Griewank K, Paschen A
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 15;20(24):6593-604
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 15;20(24):6593-604
MHC class I loss is a frequent mechanism of immune escape in papillary thyroid cancer that is reversed by interferon and selumetinib treatment in vitro.
Angell TE, Lechner MG, Jang JK, LoPresti JS, Epstein AL
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 1;20(23):6034-44
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Dec 1;20(23):6034-44
Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells.
Josson S, Matsuoka Y, Gururajan M, Nomura T, Huang WC, Yang X, Lin JT, Bridgman R, Chu CY, Johnstone PA, Zayzafoon M, Hu P, Zhau H, Berel D, Rogatko A, Chung LW
PloS one 2013;8(7):e68366
PloS one 2013;8(7):e68366
MR1B, a natural spliced isoform of the MHC-related 1 protein, is expressed as homodimers at the cell surface and activates MAIT cells.
Lion J, Debuysscher V, Wlodarczyk A, Hodroge A, Serriari NE, Choteau L, Ouled-haddou H, Plistat M, Lassoued K, Lantz O, Treiner E
European journal of immunology 2013 May;43(5):1363-73
European journal of immunology 2013 May;43(5):1363-73
HLA engineering of human pluripotent stem cells.
Riolobos L, Hirata RK, Turtle CJ, Wang PR, Gornalusse GG, Zavajlevski M, Riddell SR, Russell DW
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Jun;21(6):1232-41
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Jun;21(6):1232-41
Activation of complement by monoclonal antibodies that target cell-associated β₂-microglobulin: implications for cancer immunotherapy.
Pokrass MJ, Liu MF, Lindorfer MA, Taylor RP
Molecular immunology 2013 Dec;56(4):549-60
Molecular immunology 2013 Dec;56(4):549-60
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free Beta-2 Microglobulin Antibody (clone BBM.1). Confirmation of Integrity and Purity of the Antibody.
