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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 16036-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16036-1-AP, RRID:AB_2227602
- Product name
- Amphiregulin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Amphiregulin antibody (Cat. #16036-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells.
Extracellular Matrix-Bound FGF2 Mediates Estrogen Receptor Signaling and Therapeutic Response in Breast Cancer.
IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.
CBX2 Regulates Proliferation and Apoptosis via the Phosphorylation of YAP in Hepatocellular Carcinoma.
CD317 Activates EGFR by Regulating Its Association with Lipid Rafts.
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Loss of KIBRA function activates EGFR signaling by inducing AREG.
Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation.
The EGF receptor ligand amphiregulin controls cell division via FoxM1.
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin.
Xiao Z, Hammes SR
iScience 2021 Nov 19;24(11):103270
iScience 2021 Nov 19;24(11):103270
Extracellular Matrix-Bound FGF2 Mediates Estrogen Receptor Signaling and Therapeutic Response in Breast Cancer.
DiGiacomo JW, Godet I, Trautmann-Rodriguez M, Gilkes DM
Molecular cancer research : MCR 2021 Jan;19(1):136-149
Molecular cancer research : MCR 2021 Jan;19(1):136-149
IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.
Cai H, Yan L, Liu N, Xu M, Cai H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790
CBX2 Regulates Proliferation and Apoptosis via the Phosphorylation of YAP in Hepatocellular Carcinoma.
Mao J, Tian Y, Wang C, Jiang K, Li R, Yao Y, Zhang R, Sun D, Liang R, Gao Z, Wang Q, Wang L
Journal of Cancer 2019;10(12):2706-2719
Journal of Cancer 2019;10(12):2706-2719
CD317 Activates EGFR by Regulating Its Association with Lipid Rafts.
Zhang G, Li X, Chen Q, Li J, Ruan Q, Chen YH, Yang X, Wan X
Cancer research 2019 May 1;79(9):2220-2231
Cancer research 2019 May 1;79(9):2220-2231
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
Kubli SP, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, Jafari SM, Snow B, Jones L, Palomero L, Thu KL, Cassetta L, Soong D, Berger T, Ramachandran P, Baniasadi SP, Duncan G, Lindzen M, Yarden Y, Herranz C, Lazaro C, Chu MF, Haight J, Tinto P, Silvester J, Cescon DW, Petit A, Pettersson S, Pollard JW, Mak TW, Pujana MA, Cappello P, Gorrini C
Proceedings of the National Academy of Sciences of the United States of America 2019 Feb 26;116(9):3604-3613
Proceedings of the National Academy of Sciences of the United States of America 2019 Feb 26;116(9):3604-3613
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, Qian M, Guo J, Xu J, Cao L, Chin YE, Coppé JP, Lam EW, Campisi J, Sun Y
Aging cell 2019 Dec;18(6):e13027
Aging cell 2019 Dec;18(6):e13027
Loss of KIBRA function activates EGFR signaling by inducing AREG.
Mussell AL, Denson KE, Shen H, Chen Y, Yang N, Frangou C, Zhang J
Oncotarget 2018 Jul 6;9(52):29975-29984
Oncotarget 2018 Jul 6;9(52):29975-29984
Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation.
Stoll SW, Stuart PE, Lambert S, Gandarillas A, Rittié L, Johnston A, Elder JT
The Journal of investigative dermatology 2016 Feb;136(2):444-452
The Journal of investigative dermatology 2016 Feb;136(2):444-452
The EGF receptor ligand amphiregulin controls cell division via FoxM1.
Stoll SW, Stuart PE, Swindell WR, Tsoi LC, Li B, Gandarillas A, Lambert S, Johnston A, Nair RP, Elder JT
Oncogene 2016 Apr 21;35(16):2075-86
Oncogene 2016 Apr 21;35(16):2075-86
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin.
Yang N, Morrison CD, Liu P, Miecznikowski J, Bshara W, Han S, Zhu Q, Omilian AR, Li X, Zhang J
Cell cycle (Georgetown, Tex.) 2012 Aug 1;11(15):2922-30
Cell cycle (Georgetown, Tex.) 2012 Aug 1;11(15):2922-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 16036-1-AP(AREG antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using AREG antibody 16036-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 16036-1-AP(AREG antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 16036-1-AP(AREG antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
