APR06249G

antibody from Leading Biology
Targeting: IL1RAP C3orf13, IL-1RAcP, IL1R3
Provider product page for APR06249G
Western blot
Immunocytochemistry

Antibody data

Product number
APR06249G - Provider product page
Provider
Leading Biology
Product name
IL-1RAcP Antibody
Antibody type
Polyclonal
Description
IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κB inducing kinae (NIK) and of NF-κB, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
IL1RAP protein structure - APR06249G shown in red.