Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 331932 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#331932, RRID:AB_2566426
- Product name
- Alexa Fluor® 700 anti-human CD335 (NKp46)
- Antibody type
- Monoclonal
- Antigen
- NKp46-Fc fusion protein
- Description
- CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Near infrared dye
- Antibody clone number
- 9.00E+02
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD56 PE and CD335 (clone 9E2) Alexa Fluor® 700 (top) or mouse IgG1, κ Alexa Fluor® 700 isotype control (bottom).
- Conjugate
- Near infrared dye