Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60157 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- NMDA÷3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human NMDA÷3.
- Description
- Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors exhibit slow kinetsis of Ca2+ ions and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ÷ 1, 2, 3, 4 and one ø subunit. The ø subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of NMDA¦Å3 pAb at 1:500 dilutionLane1:SKOVCAR whole cell lysateLane2:HEK293T whole cell lysateLane3:sp2/0 whole cell lysate