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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 17561-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17561-1-AP, RRID:AB_2188463
- Product name
- Sur-8 antibody
- Antibody type
- Polyclonal
- Description
- Sur-8 antibody (Cat. #17561-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.
SHOC2 Is a Critical Modulator of Sensitivity to EGFR-TKIs in Non-Small Cell Lung Cancer Cells.
VCP/p97 controls signals of the ERK1/2 pathway transmitted via the Shoc2 scaffolding complex: novel insights into IBMPFD pathology.
Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.
Shoc2-tranduced ERK1/2 motility signals--Novel insights from functional genomics.
Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.
HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.
Wilson P, Abdelmoti L, Norcross R, Jang ER, Palayam M, Galperin E
Journal of cell science 2021 Nov 1;134(21)
Journal of cell science 2021 Nov 1;134(21)
SHOC2 Is a Critical Modulator of Sensitivity to EGFR-TKIs in Non-Small Cell Lung Cancer Cells.
Terai H, Hamamoto J, Emoto K, Masuda T, Manabe T, Kuronuma S, Kobayashi K, Masuzawa K, Ikemura S, Nakayama S, Kawada I, Suzuki Y, Takeuchi O, Suzuki Y, Ohtsuki S, Yasuda H, Soejima K, Fukunaga K
Molecular cancer research : MCR 2021 Feb;19(2):317-328
Molecular cancer research : MCR 2021 Feb;19(2):317-328
VCP/p97 controls signals of the ERK1/2 pathway transmitted via the Shoc2 scaffolding complex: novel insights into IBMPFD pathology.
Jang H, Jang ER, Wilson PG, Anderson D, Galperin E
Molecular biology of the cell 2019 Jul 1;30(14):1655-1663
Molecular biology of the cell 2019 Jul 1;30(14):1655-1663
Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.
Lee P, Jiang S, Li Y, Yue J, Gou X, Chen SY, Zhao Y, Schober M, Tan M, Wu X
The EMBO journal 2017 Jul 3;36(13):1963-1980
The EMBO journal 2017 Jul 3;36(13):1963-1980
Shoc2-tranduced ERK1/2 motility signals--Novel insights from functional genomics.
Jeoung M, Jang ER, Liu J, Wang C, Rouchka EC, Li X, Galperin E
Cellular signalling 2016 May;28(5):448-459
Cellular signalling 2016 May;28(5):448-459
Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5.
Jang ER, Jang H, Shi P, Popa G, Jeoung M, Galperin E
Journal of cell science 2015 Dec 1;128(23):4428-41
Journal of cell science 2015 Dec 1;128(23):4428-41
HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.
Jang ER, Shi P, Bryant J, Chen J, Dukhande V, Gentry MS, Jang H, Jeoung M, Galperin E
Molecular and cellular biology 2014 Oct 1;34(19):3579-93
Molecular and cellular biology 2014 Oct 1;34(19):3579-93
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.
Harmon RM, Simpson CL, Johnson JL, Koetsier JL, Dubash AD, Najor NA, Sarig O, Sprecher E, Green KJ
The Journal of clinical investigation 2013 Apr;123(4):1556-70
The Journal of clinical investigation 2013 Apr;123(4):1556-70
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 17561-1-AP(SHOC2 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Sur-8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Sur-8. This antibody recognizes human,mouse,rat antigen. The Sur-8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
