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- References [4]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500706 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) antibody
- Antibody type
- Polyclonal
- Antigen
- SHOC2 antibody was raised against a 21 amino acid peptide near the amino terminus ofhuman SHOC2.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity.
The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf.
soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling.
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans.
Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, Fried M, McCormick F
Molecular cell 2006 Apr 21;22(2):217-30
Molecular cell 2006 Apr 21;22(2):217-30
The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf.
Li W, Han M, Guan KL
Genes & development 2000 Apr 15;14(8):895-900
Genes & development 2000 Apr 15;14(8):895-900
soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling.
Selfors LM, Schutzman JL, Borland CZ, Stern MJ
Proceedings of the National Academy of Sciences of the United States of America 1998 Jun 9;95(12):6903-8
Proceedings of the National Academy of Sciences of the United States of America 1998 Jun 9;95(12):6903-8
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans.
Sieburth DS, Sun Q, Han M
Cell 1998 Jul 10;94(1):119-30
Cell 1998 Jul 10;94(1):119-30
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SHOC2 in Jurkat cell lysate with AP30776PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of SHOC2 in human spleen tissue with AP30776PU-N at 5 ?g/ml.
